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Article

WNT5A-NFAT Signaling Mediates Resistance to Apoptosis in Pancreatic Cancer

1 Jan 2013

Abstract excerpt

INTRODUCTION: WNT5A belongs to the Wnt family of secreted signaling molecules. Using transcriptional profiling, we previously identified WNT5A as target of the antiapoptotic transcription factor CUX1 and demonstrated high expression levels in pancreatic cancer. However, the impact of WNT5A on drug resistance and the signaling pathways employed by WNT5A remain to be elucidated. OBJECTIVES: This project aims to...

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PMID: 23359789
DOI: 10.1593/neo.121312

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