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Article

Fzd7/Wnt7b signaling contributes to stemness and chemoresistance in pancreatic cancer

1 May 2021

Abstract excerpt

Abstract Mining databases and data obtained from assays on human specimens had shown that Fzd7 is closely associated with Wnt7b, that Fzd7/Wnt7b expression is upregulated in pancreatic cancer tissues compared with normal tissues, and its expression is negatively correlated with survival. Fzd7/Wnt7b knockdown in Capan‐2 and Panc‐1 cells reduced the proliferative capacity of pancreatic cancer stem cells (PCSCs),...

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PMID: 33934523
DOI: 10.1002/cam4.3819

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