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Article

Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons.

PLoS genetics - 1 Jan 2013

Lacombe Julie, Hanley Olivia, Jung Heekyung, Philippidou Polyxeni, Surmeli Gulsen, Grinstein Jonathan, Dasen Jeremy S

Abstract excerpt

A critical step in the assembly of the neural circuits that control tetrapod locomotion is the specification of the lateral motor column (LMC), a diverse motor neuron population targeting limb musculature. Hox6 paralog group genes have been implicated as key determinants of LMC fate at forelimb l...

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Identifiers

PMID: 23359544
DOI: 10.1371/journal.pgen.1003184
PMCID: PMC3554521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23359544-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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