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Article

AbCD: arbitrary coverage design for sequencing-based genetic studies.

Bioinformatics (Oxford, England) - 15 Mar 2013

Kang Jian, Huang Kuan-Chieh, Xu Zheng, Wang Yunfei, Abecasis Gonçalo R, Li Yun

Abstract excerpt

Recent advances in sequencing technologies have revolutionized genetic studies. Although high-coverage sequencing can uncover most variants present in the sequenced sample, low-coverage sequencing is appealing for its cost effectiveness. Here, we present AbCD (arbitrary coverage design) to aid the design of sequencing-based studies. AbCD is a user-friendly interface providing pre-estimated effective sample sizes,...

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Identifiers

PMID: 23357921
DOI: 10.1093/bioinformatics/btt041
PMCID: PMC3597143

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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