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Article

Long-range PCR based sequencing of the highly homologous genes, SFTPA1 and SFTPA2.

Molecular and cellular probes - 1 Jan 2000

Horton Christopher J, Mitui Midori, Leos Nora K, Garcia Christine Kim, Park Jason Y

Abstract excerpt

In humans, Surfactant Protein A exists as two highly homologous genetic isoforms, SFTPA1 and SFTPA2. Mutations in these two genes are associated with idiopathic pulmonary fibrosis (IPF) and lung cancer. We have developed a Sanger DNA sequencing assay which utilizes long-range PCR to detect mutations in these two genes.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23354021
DOI: 10.1016/j.mcp.2013.01.001

Genes

SFTPA1
SFTPA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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