Article
A single round PCR method for genotyping human surfactant protein (SP)-A1, SP-A2 and SP-D gene alleles.
Tissue antigens - 1 Apr 2003
Pantelidis P, Lagan A L, Davies J C, Welsh K I, du Bois R M
Abstract excerpt
The genes coding for the human surfactant proteins (SP)-A and SP-D are located on chromosome 10q22-q23.1. SP-D is the product of a single gene whereas SP-A is the product of two highly homologous genes SP-A1 and SP-A2. Several single nucleotide polymorphisms (SNP) are present in the SP-A1, SP-A2 and SP-D genes. Because of this high degree of sequence homology between the SP-A1 and SP-A2 genes, current genetic...
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