Article
Inflammation in the setting of chronic allograft dysfunction post-kidney transplant: phenotype and genotype.
Clinical transplantation - 1 Jan 2000
Israni Ajay K, Leduc Robert, Jacobson Pamala A, Wildebush Winston, Guan Weihua, Schladt David, Matas Arthur J, Oetting William S
Abstract excerpt
BACKGROUND: Chronic allograft dysfunction (CGD) is a common outcome in kidney transplants, but its pathogenesis is unclear. We investigated the CGD phenotype and single-nucleotide polymorphisms (SNPs) associated with CGD. METHOD: This prospective study enrolled 2336 transplants from seven transplant centers in North America. CGD was defined as a >25% rise in serum creatinine relative to a three-month...
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