Article
Massively parallel sequencing for chromosomal abnormality testing in trophectoderm cells of human blastocysts.
Biology of reproduction - 1 Mar 2013
Yin XuYang, Tan Ke, Vajta Gábor, Jiang Hui, Tan YueQiu, Zhang ChunLei, Chen Fang, Chen ShengPei, Zhang ChunSheng, Pan XiaoYu, Gong Chun, Li XuChao, Lin ChuYu, Gao Ya, Liang Yu, Yi Xin, Mu Feng, Zhao LiJian, Peng HuanHuan, Xiong Bo, Zhang ShuoPing, Cheng DeHua, Lu GuangXiu, Zhang XiuQing, Lin Ge, Wang Wei
Abstract excerpt
Preimplantation genetic diagnosis and screening are widely accepted for chromosomal abnormality identification to avoid transferring embryos with genetic defects. Massively parallel sequencing (MPS) is a rapidly developing approach for genome analysis with increasing application in clinical practice. The purpose of this study was to use MPS for identification of aneuploidies and unbalanced chromosomal...
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