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Article

Clinical outcome of preimplantation genetic diagnosis and screening using next generation sequencing

1 Dec 2014

Abstract excerpt

BACKGROUND: Next generation sequencing (NGS) is now being used for detecting chromosomal abnormalities in blastocyst trophectoderm (TE) cells from in vitro fertilized embryos. However, few data are available regarding the clinical outcome, which provides vital reference for further application of the methodology. Here, we present a clinical evaluation of NGS-based preimplantation genetic diagnosis/screening...

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PMID: 25685330
DOI: 10.1186/2047-217x-3-30

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