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Article

The LINC complex is essential for hearing.

The Journal of clinical investigation - 1 Feb 2013

Horn Henning F, Brownstein Zippora, Lenz Danielle R, Shivatzki Shaked, Dror Amiel A, Dagan-Rosenfeld Orit, Friedman Lilach M, Roux Kyle J, Kozlov Serguei, Jeang Kuan-Teh, Frydman Moshe, Burke Brian, Stewart Colin L, Avraham Karen B

Abstract excerpt

Hereditary hearing loss is the most common sensory deficit. We determined that progressive high-frequency hearing loss in 2 families of Iraqi Jewish ancestry was due to homozygosity for the protein truncating mutation SYNE4 c.228delAT. SYNE4, a gene not previously associated with hearing loss, en...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23348741
DOI: 10.1172/JCI66911
PMCID: PMC3561815

Genes

SUN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23348741-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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