Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of LIPC and advanced age-related macular degeneration.

Eye (London, England) - 1 Feb 2013

Lee J, Zeng J, Hughes G, Chen Y, Grob S, Zhao L, Lee C, Krupa M, Quach J, Luo J, Zeng J, Wei X, Zhang X, Zhu J, Duan Y, Ferreyra H, Goldbaum M, Haw W, Shaw P X, Tang L, Zhang K

Abstract excerpt

PURPOSE: To determine whether there is an association between hepatic lipase (LIPC) and age-related macular degeneration (AMD) in two independent Caucasian cohorts. METHODS: A discovery cohort of 1626 patients with advanced AMD and 859 normal controls and a replication cohort of 2159 cases and 1150 controls were genotyped for two single-nucleotide polymorphisms (SNPs) in the promoter region of LIPC. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alleles

Share to Cohort Studies

Share to Gene Frequency

Share to Lipase

Share to Macular Degeneration

Share to Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 23348725
DOI: 10.1038/eye.2012.276
PMCID: PMC3574263

Genes

LIPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of LIPC and advanced age-related macular degeneration.PMID 23348725Read ↗

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).Semantic proximity Read ↗

Associations of smoking, body mass index, dietary lutein, and the LIPC gene variant rs10468017 with advanced age-related macular degeneration.Semantic proximity Read ↗

The relationship between hepatic lipase gene variant and advanced age-related macular degeneration: a meta-analysis.Semantic proximity Read ↗

The Association between LIPC rs493258 Polymorphism and the Susceptibility to Age-Related Macular Degeneration.Semantic proximity Read ↗

Serum lipid biomarkers and hepatic lipase gene associations with age-related macular degeneration.Semantic proximity Read ↗

CETP/LPL/LIPC gene polymorphisms and susceptibility to age-related macular degeneration.Semantic proximity Read ↗

CETP Gene may be Associated with Advanced Age-Related Macular Degeneration in the Chinese Population.Semantic proximity Read ↗

Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration.Semantic proximity Read ↗

The association study of lipid metabolism gene polymorphisms with AMD identifies a protective role for APOE-E2 allele in the wet form in a Northern Spanish population.Semantic proximity Read ↗

Associations of cholesteryl ester transfer protein (CETP) gene variants with predisposition to age-related macular degeneration.Semantic proximity Read ↗

[Mendelian randomization study of the relationship between high-density lipoprotein cholesterol and age-related macular degeneration].Semantic proximity Read ↗

Genetic Variants and Systemic Complement Activation Levels Are Associated With Serum Lipoprotein Levels in Age-Related Macular Degeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.