Article
Epigenome-wide association study reveals longitudinally stable DNA methylation differences in CD4+ T cells from children with IgE-mediated food allergy.
Epigenetics - 1 Jul 2014
Martino David, Joo Jihoon E, Sexton-Oates Alexandra, Dang Thanh, Allen Katrina, Saffery Richard, Prescott Susan
Abstract excerpt
UNLABELLED: Food allergy is mediated by a combination of genetic and environmental risk factors, potentially mediated by epigenetic mechanisms. CD4+ T-cells are key drivers of the allergic response, and may therefore harbor epigenetic variation in association with the disease phenotype. Here we r...
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