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Article

Epigenome-wide association study reveals longitudinally stable DNA methylation differences in CD4+ T cells from children with IgE-mediated food allergy.

Epigenetics - 1 Jul 2014

Martino David, Joo Jihoon E, Sexton-Oates Alexandra, Dang Thanh, Allen Katrina, Saffery Richard, Prescott Susan

Abstract excerpt

UNLABELLED: Food allergy is mediated by a combination of genetic and environmental risk factors, potentially mediated by epigenetic mechanisms. CD4+ T-cells are key drivers of the allergic response, and may therefore harbor epigenetic variation in association with the disease phenotype. Here we retrospectively examined genome-wide DNA methylation profiles (~450,000 CpGs) from CD4+ T-cells on a birth cohort of 12...

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Source

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Identifiers

PMID: 24762976
DOI: 10.4161/epi.28945
PMCID: PMC4143415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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