Article
Morphological development and cytochrome c oxidase activity in Streptomyces lividans are dependent on the action of a copper bound Sco protein.
Open biology - 23 Jan 2013
Blundell Katie L I M, Wilson Michael T, Svistunenko Dimitri A, Vijgenboom Erik, Worrall Jonathan A R
Abstract excerpt
Copper has an important role in the life cycle of many streptomycetes, stimulating the developmental switch between vegetative mycelium and aerial hyphae concomitant with the production of antibiotics. In streptomycetes, a gene encoding for a putative Sco-like protein has been identified and is part of an operon that contains two other genes predicted to handle cellular copper. We report on the Sco-like protein...
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