Article
A structural bioinformatics approach for identifying proteins predisposed to bind linear epitopes on pre-selected target proteins.
Protein engineering, design & selection : PEDS - 1 Apr 2013
Choi Eun Jung, Jacak Ron, Kuhlman Brian
Abstract excerpt
We have developed a protocol for identifying proteins that are predisposed to bind linear epitopes on target proteins of interest. The protocol searches through the protein database for proteins (scaffolds) that are bound to peptides with sequences similar to accessible, linear epitopes on the target protein. The sequence match is considered more significant if residues calculated to be important in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
