Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Postnatal growth defects in mice with constitutive depletion of central serotonin.

ACS chemical neuroscience - 16 Jan 2013

Narboux-Nême Nicolas, Angenard Gaelle, Mosienko Valentina, Klempin Friederike, Pitychoutis Pothitos M, Deneris Evan, Bader Michael, Giros Bruno, Alenina Natalia, Gaspar Patricia

Abstract excerpt

Although the trophic actions of serotonin (5-HT) are well established, only few developmental defects have been reported in mouse strains with constitutive hyposerotonergia. We analyzed postnatal growth and cortical development in three different mutant mouse strains with constitutive reductions in central 5-HT levels. We compared two previously published mouse strains with severe (-95%) depletions of 5-HT, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Chemistry
Share to Cerebral Cortex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fetal Development

Share to Growth Disorders

Share to Mice, Knockout

Share to Serotonin

Share to Tryptophan Hydroxylase

Source

Open in PubMed Open full text

Identifiers

PMID: 23336056
DOI: 10.1021/cn300165x
PMCID: PMC3547491

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Postnatal growth defects in mice with constitutive depletion of central serotonin.PMID 23336056Read ↗

Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation.Semantic proximity Read ↗

Genetic Models of Serotonin (5‐HT) Depletion: What do They Tell Us About the Developmental Role of 5‐HT?Semantic proximity Read ↗

Chronic central serotonin depletion attenuates ventilation and body temperature in young but not adult Tph2 knockout rats.Semantic proximity Read ↗

[Genetic models to understand how serotonin acts during development].Semantic proximity Read ↗

Generation of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain Serotonin.Semantic proximity Read ↗

Embryonic and postnatal development of the serotonergic raphe system and its target regions in 5-HT1A receptor deletion or overexpressing mouse mutants.Semantic proximity Read ↗

Modeling early cortical serotonergic deficits in autism.Semantic proximity Read ↗

Mirtazapine treatment in a young female mouse model of Rett syndrome identifies time windows for the rescue of early phenotypes.Semantic proximity Read ↗

Mirtazapine treatment in a young female mouse model of Rett syndrome identifies time windows for the rescue of early phenotypes during developmentSemantic proximity Read ↗

Acute and crucial requirement for MeCP2 function upon transition from early to late adult stages of brain maturation.Semantic proximity Read ↗

Selective genetic disruption of dopaminergic, serotonergic and noradrenergic neurotransmission: insights into motor, emotional and addictive behaviour.Semantic proximity Read ↗

Severe deficits in 5-HT2A -mediated neurotransmission in BDNF conditional mutant mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.