Article
A pathway for unicellular tube extension depending on the lymphatic vessel determinant Prox1 and on osmoregulation.
Nature cell biology - 1 Feb 2013
Kolotuev Irina, Hyenne Vincent, Schwab Yannick, Rodriguez David, Labouesse Michel
Abstract excerpt
The mechanisms regulating the extension of small unicellular tubes remain poorly defined. Here we identify several steps in Caenorhabditis elegans excretory canal growth, and propose a model for lumen extension. Our results suggest that the basal and apical excretory membranes grow sequentially:...
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