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Article

Role of β2 adrenoreceptor gene polymorphism in the formation of cold hyperreactivity of the airways in asthmatics.

Bulletin of experimental biology and medicine - 1 Nov 2012

Naumov D E, Perelman Ju M, Maksimov V N, Kolosov V P, Voevoda M I, Xiandong Zhou, Li Qi, Qi Li

Abstract excerpt

The relationship between β(2)-adrenoreceptor gene Arg16Gly polymorphism and bronchial cold reactivity has been studied. Genotype Arg16Arg and allele Arg16 carriership is associated with the development of cold bronchospasm in asthmatics. In addition, a significant reduction of 3,5'-cyclic adenosine monophosphate (cAMP) level has been recorded in Arg16Arg homozygotes on minute 30 after cold provocation in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23330094
DOI: 10.1007/s10517-012-1878-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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