Article
[Expression of SDHB, EPAS1 and MIB-1 in Zuckerkandl paragangliomas].
Zhonghua yi xue za zhi - 27 Nov 2012
Deng Jian-hua, Li Han-zhong, Zhang Yu-shi, Xu Wei-feng, Cui Quan-cai
Abstract excerpt
OBJECTIVE: To explore the significance of succinate dehydrogenase B (SDHB) mutation and EPAS1 overexpression in Zuckerkandl paragangliomas (PGL) and examine their correlations with malignant infiltration and metastasis. METHODS: From March 2008 to July 2011, the clinical profiles of 16 Zuckerkandl PGL patients were analyzed retrospectively. For increased diagnostic specificity, a complex immunohistochemical panel...
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