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Article

Genetic and epigenetic patterns in patients with the head-and-neck paragangliomas associate with differential clinical characteristics.

Journal of cancer research and clinical oncology - 1 Jun 2017

Chen Hongsai, Zhu Weidong, Li Xiye, Xue Lu, Wang Zhaoyan, Wu Hao

Abstract excerpt

PURPOSE: In addition to genetic alterations, the importance of a CpG island methylator phenotype, characterized by methylation of multiple tumour-suppressor genes (TSGs), has been acknowledged in many cancer types. This study was done to determine the impact of genetic and epigenetic patterns on the clinical characteristics of the head and neck paragangliomas (HNPGLs). METHODS: The retrospective study examined a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28255624
DOI: 10.1007/s00432-017-2355-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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