Article
Cardiac paragangliomas: A case series with clinicopathologic features and succinate dehydrogenase B immunostaining.
Annals of diagnostic pathology - 1 Apr 2020
Alakeel Fadi, Al Sannaa Ghadah, Ibarra-Cortez Sergio H, Reardon Michael J, Czerniak Bogdan, Chan Edward Y, Ro Jae
Abstract excerpt
Cardiac paragangliomas (PGs) are very rare tumors that comprise less than 1% of all cardiac tumors. PGs can occur sporadically, but inherited syndromes may also play a role in the development of PGs. Approximately one-third of PGs are associated with mutations in the succinate dehydrogenase (SDH) complex, specifically SDHB, as part of syndrome-associated PGs or sporadic PGs. SDH mutations have been assessed by...
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