Article
Negative regulation of human immune deficiency virus replication in monocytes. Distinctions between restricted and latent expression in THP-1 cells.
The Journal of experimental medicine - 1 May 1990
Mikovits J A, Raziuddin, Gonda M, Ruta M, Lohrey N C, Kung H F, Ruscetti F W
Abstract excerpt
In THP-1 monocytoid cells infected with HIV, viral expression can be regulated in several ways: (a) latency (no viral expression); (b) restricted expression (chronic low-level viral expression with little or no detectable virus released); and (c) continuous production. In cells with restricted HI...
Topics
- Antigens, Viral
- Cell Line
- Cell Survival
- DNA, Viral
- HIV-1
- Humans
- Microscopy, Electron
- Monocytes
- Phenotype
- Polymerase Chain Reaction
- RNA, Viral
- Repetitive Sequences, Nucleic Acid
- Virus Replication