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Article

Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage

9 Apr 2010

Abstract excerpt

The introduction of the highly active antiretroviral therapy (HAART) has greatly improved survival. However, these treatments fail to definitively cure the patients and unveil the presence of quiescent HIV-1 reservoirs like cells from monocyte-macrophage lineage. A purge, or at least a significant reduction of these long lived HIV-1 reservoirs will be needed to raise the hope of the viral eradication. This review...

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PMID: 20380694
DOI: 10.1186/1742-4690-7-32

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