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Article

The Cobas AmpliPrep/Cobas TaqMan HCV test, version 2.0, real-time PCR assay accurately quantifies hepatitis C virus genotype 4 RNA.

Journal of clinical microbiology - 1 Apr 2013

Chevaliez Stéphane, Bouvier-Alias Magali, Rodriguez Christophe, Soulier Alexandre, Poveda Jean-Dominique, Pawlotsky Jean-Michel

Abstract excerpt

Accurate hepatitis C virus (HCV) RNA quantification is mandatory for the management of chronic hepatitis C therapy. The first-generation Cobas AmpliPrep/Cobas TaqMan HCV test (CAP/CTM HCV) underestimated HCV RNA levels by >1-log10 international units/ml in a number of patients infected with HCV genotype 4 and occasionally failed to detect it. The aim of this study was to evaluate the ability of the Cobas...

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Identifiers

PMID: 23325825
DOI: 10.1128/JCM.02004-12
PMCID: PMC3666793

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