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Article

Development of a second version of the Cobas AmpliPrep/Cobas TaqMan hepatitis C virus quantitative test with improved genotype inclusivity.

Journal of clinical microbiology - 1 Sept 2011

Vermehren Johannes, Colucci Giuseppe, Gohl Peter, Hamdi Nabila, Abdelaziz Ahmed Ihab, Karey Ursula, Thamke Diana, Zitzer Heike, Zeuzem Stefan, Sarrazin Christoph

Abstract excerpt

Hepatitis C virus (HCV) RNA measurement has been facilitated by the introduction of real-time PCR-based assays with low limits of detection and broad dynamic ranges for quantification. In the present study, the performance of two second-version prototypes of the Cobas AmpliPrep/Cobas TaqMan HCV Quantitative Test (CAP/CTM v2) with decreased sample input volume and improved genotype inclusivity was investigated. A...

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Identifiers

PMID: 21752967
DOI: 10.1128/JCM.00602-11
PMCID: PMC3165622

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