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The Cobas AmpliPrep-Cobas TaqMan real-time polymerase chain reaction assay fails to detect hepatitis C virus RNA in highly viremic genotype 4 clinical samples #

9 Dec 2008

Abstract excerpt

Accurate hepatitis C virus (HCV) RNA quantification is essential for the current and future management of chronic hepatitis C therapy. Assays based on real-time polymerase chain reaction (PCR) are now widely used in clinical virology laboratories.1 Two real-time PCR platforms are commercially available: Cobas TaqMan, which can be used with automated sample preparation in the Cobas AmpliPrep system [Cobas...

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PMID: 19330876
DOI: 10.1002/hep.22767

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