Article
Second-generation Cobas AmpliPrep/Cobas TaqMan HCV quantitative test for viral load monitoring: a novel dual-probe assay design.
Journal of clinical microbiology - 1 Feb 2013
Zitzer Heike, Heilek Gabrielle, Truchon Karine, Susser Simone, Vermehren Johannes, Sizmann Dorothea, Cobb Bryan, Sarrazin Christoph
Abstract excerpt
Hepatitis C virus (HCV) RNA viral load (VL) monitoring is a well-established diagnostic tool for the management of chronic hepatitis C patients. HCV RNA VL results are used to make treatment decisions with the goal of therapy to achieve an undetectable VL result. Therefore, a sensitive assay with high specificity in detecting and accurately quantifying HCV RNA across genotypes is critical. Additionally, a lower...
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