Article
17p12 Influences Hematoma Volume and Outcome in Spontaneous Intracerebral Hemorrhage.
Stroke - 1 Jul 2018
Marini Sandro, Devan William J, Radmanesh Farid, Miyares Laura, Poterba Timothy, Hansen Björn M, Norrving Bo, Jimenez-Conde Jordi, Giralt-Steinhauer Eva, Elosua Roberto, Cuadrado-Godia Elisa, Soriano Carolina, Roquer Jaume, Kourkoulis Christina E, Ayres Alison M, Schwab Kristin, Tirschwell David L, Selim Magdy, Brown Devin L, Silliman Scott L, Worrall Bradford B, Meschia James F, Kidwell Chelsea S, Montaner Joan, Fernandez-Cadenas Israel, Delgado Pilar, Greenberg Steven M, Lindgren Arne, Matouk Charles, Sheth Kevin N, Woo Daniel, Anderson Christopher D, Rosand Jonathan, Falcone Guido J
Abstract excerpt
BACKGROUND AND PURPOSE: Hematoma volume is an important determinant of clinical outcome in spontaneous intracerebral hemorrhage (ICH). We performed a genome-wide association study (GWAS) of hematoma volume with the aim of identifying novel biological pathways involved in the pathophysiology of primary brain injury in ICH. METHODS: We conducted a 2-stage (discovery and replication) case-only genome-wide...
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