Article
Cell interactions control the direction of outgrowth, branching and fasciculation of the HSN axons of Caenorhabditis elegans.
Development (Cambridge, England) - 1 Mar 1993
Garriga G, Desai C, Horvitz H R
Abstract excerpt
The two serotonergic HSN motor neurons of the nematode Caenorhabditis elegans innervate the vulval muscles and stimulate egg laying by hermaphrodites. By analyzing mutant and laser-operated animals, we find that both epithelial cells of the developing vulva and axons of the ventral nerve cord are required for HSN axonal guidance. Vulval precursor cells help guide the growth cone of the emerging HSN axon to the...
Read the complete abstract on PubMedTopics
- Animals
- Axons
- Caenorhabditis elegans
- Cell Communication
- Female
- Immunohistochemistry
- Microscopy, Fluorescence
