Article
Functional interplay between the cell cycle and cell phenotypes.
Integrative biology : quantitative biosciences from nano to macro - 1 Mar 2013
Chen Wei-Chiang, Wu Pei-Hsun, Phillip Jude M, Khatau Shyam B, Choi Jae Min, Dallas Matthew R, Konstantopoulos Konstantinos, Sun Sean X, Lee Jerry S H, Hodzic Didier, Wirtz Denis
Abstract excerpt
Cell cycle distribution of adherent cells is typically assessed using flow cytometry, which precludes the measurements of many cell properties and their cycle phase in the same environment. Here we develop and validate a microscopy system to quantitatively analyze the cell-cycle phase of thousands of adherent cells and their associated cell properties simultaneously. This assay demonstrates that...
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