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Alterations in mtDNA: a qualitative and quantitative study associated with cervical cancer development.

Gynecologic oncology - 1 Apr 2013

Warowicka A, Kwasniewska A, Gozdzicka-Jozefiak A

Abstract excerpt

OBJECTIVE: High-risk human papillomaviruses are the causative agent of cervical carcinogenesis. Additionally, a number of other unknown factors are also instrumental in the development of cancer. The aim of this present study was the analysis of the mutations in the D-loop region of mitochondrial DNA, and 4.997 bp deletion during cervical cancer development. Our research also extended to the relationship between...

Topics

Adult
DNA, Mitochondrial
Female
Gene Dosage
Humans
Middle Aged
Mutation
Papillomaviridae
Precancerous Conditions
Reactive Oxygen Species
Superoxide Dismutase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Uterine Cervical Neoplasms

Source

Identifiers

PMID: 23319113
DOI: 10.1016/j.ygyno.2013.01.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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