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Article

Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk.

The American journal of psychiatry - 1 Mar 2013

Ross Randal G, Hunter Sharon K, McCarthy Lizbeth, Beuler Julie, Hutchison Amanda K, Wagner Brandie D, Leonard Sherry, Stevens Karen E, Freedman Robert

Abstract excerpt

OBJECTIVE: Deficient cerebral inhibition is a pathophysiological brain deficit related to poor sensory gating and attention in schizophrenia and other disorders. Cerebral inhibition develops perinatally, influenced by genetic and in utero factors. Amniotic choline activates fetal α7-nicotinic ace...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23318559
DOI: 10.1176/appi.ajp.2012.12070940
PMCID: PMC3640283

Genes

CHRNA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23318559-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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