Article
Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia.
Psychopharmacology - 1 Jun 2004
Martin Laura F, Kem William R, Freedman Robert
Abstract excerpt
RATIONALE AND OBJECTIVE: Auditory sensory gating, a biological measurement of the ability to suppress the evoked response to the second of two auditory stimuli, is diminished in people with schizophrenia. Deficits in sensory gating are associated with attentional impairment, and may contribute to cognitive symptoms and perceptual disturbances. This inhibitory process, which involves the alpha(7) nicotinic...
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