Article
CFTR-mutation specific applications of CFTR-directed monoclonal antibodies.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Sept 2013
van Meegen M A, Terheggen S W J, Koymans K J, Vijftigschild L A W, Dekkers J F, van der Ent C K, Beekman J M
Abstract excerpt
BACKGROUND: Over the last decade novel monoclonal CFTR-specific antibodies have been developed. We here present a paired analysis to detect wild-type and mutant CFTR using Western blot analysis, flow cytometry and confocal microscopy in several cellular expression systems. METHODS: The following...
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