Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GSTM1 and GSTT1 polymorphism and susceptibility to esophageal cancer in high- and low-risk regions of India.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2013

Sharma Anita, Das Bhudev Chander, Sehgal Ashok, Mehrotra Ravi, Kar Premashish, Sardana Sarita, Phukan Rup, Mahanta Jagdish, Purkayastha Joydeep, Saxena Sunita, Kapur Sujala, Chatterjee Indranil, Sharma Joginder Kumar

Abstract excerpt

Glutathione transferases, a super family of dimeric phase II metabolic enzymes play a vital role in biotransformation of many substances. This study evaluates the influence of genetic polymorphism of GSTM1 and GSTT1 gene loci on esophageal cancer risk in Assam and Delhi from India. DNA from blood samples of esophageal cancer cases (203,112) and controls (286,150) from Assam and Delhi, respectively, were...

Topics

Join the communities discussing this publication.

Alcohol Drinking
Carcinoma, Squamous Cell
Esophageal Neoplasms
Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glutathione Transferase

Tobacco, Smokeless

Source

Identifiers

PMID: 23749488
DOI: 10.1007/s13277-013-0897-6

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GSTM1 and GSTT1 polymorphism and susceptibility to esophageal cancer in high- and low-risk regions of India.PMID 23749488Read ↗

GSTT1, GSTM1 and GSTP1 genetic polymorphisms and interaction with tobacco, alcohol and occupational exposure in esophageal cancer patients from North IndiaSemantic proximity Read ↗

Genetic polymorphisms of GSTM1 and GSTT1 genes in Delhi and comparison with other Indian and global populations.Semantic proximity Read ↗

GSTs genetic polymorphism, gene-environment interaction and association with gallbladder cancer risk in North Indian population: A case-controlled study.Semantic proximity Read ↗

Association between GSTM1 and GSTT1 polymorphisms and esophageal squamous cell carcinoma: results from a case-control study in Kashmir, India.Semantic proximity Read ↗

Null Glutathione S-transferase T1 and M1 genotypes and oral cancer susceptibility in China and India--a meta-analysis.Semantic proximity Read ↗

Null genotype of GSTT1 may be associated with esophageal cancer risk: a meta-analysis in Chinese individuals.Semantic proximity Read ↗

GSTM1 and GSTT1 Gene Polymorphisms, Gene-Gene Interaction, and Esophageal Carcinoma Risk: Evidence from an Updated Meta-Analysis.Semantic proximity Read ↗

Polymorphisms of glutathione-S-transferase genes and the risk of aerodigestive tract cancers in the Northeast Indian population.Semantic proximity Read ↗

Association of DNA repair and xenobiotic pathway gene polymorphisms with genetic susceptibility to gastric cancer patients in West Bengal, India.Semantic proximity Read ↗

GSTM1 and GSTT1 allele frequencies among various Indian and non-Indian ethnic groups.Semantic proximity Read ↗

Prevalence of CYP1A1 and GST polymorphisms in the population of northeastern India and susceptibility of oral cancer.Semantic proximity Read ↗

Genetic polymorphisms of glutathione-S-transferase genes (GSTM1, GSTT1 and GSTP1) and upper aerodigestive tract cancer risk among smokers, tobacco chewers and alcoholics in an Indian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.