Article
Global transcriptional profiling of the postmortem brain of a patient with G114V genetic Creutzfeldt-Jakob disease.
International journal of molecular medicine - 1 Mar 2013
Tian Chan, Liu Di, Chen Chen, Xu Yin, Gong Han-Shi, Chen Cao, Shi Qi, Zhang Bao-Yun, Han Jun, Dong Xiao-Ping
Abstract excerpt
Familial or genetic Creutzfeldt-Jakob disease (fCJD or gCJD) is an inherent human prion disease caused by mutation of the prion protein gene (PRNP). In the present study, global expression patterns of the parietal cortex from a patient with G114V gCJD were analyzed using the Affymetrix Human Geno...
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