Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA Double Strand Break Repair: A Radiation Perspective

11 Jan 2013

Abstract excerpt

SIGNIFICANCE: Ionizing radiation (IR) can induce a wide range of unique deoxyribonucleic acid (DNA) lesions due to the spatiotemporal correlation of the ionization produced. Of these, DNA double strand breaks (DSBs) play a key role. Complex mechanisms and sophisticated pathways are available within cells to restore the integrity and sequence of the damaged DNA molecules. RECENT ADVANCES: Here we review the main...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer therapeutics and mechanisms
Share to DNA Repair Mechanisms
Share to PARP inhibition in cancer therapy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23311752
DOI: 10.1089/ars.2012.5151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 16 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA Double Strand Break Repair: A Radiation PerspectivePMID 23311752Read ↗

A historical reflection on our understanding of radiation-induced DNA double strand break repair in somatic mammalian cells; interfacing the past with the presentSemantic proximity Read ↗

Ionizing Radiation-Induced DNA Damage, Response, and RepairSemantic proximity Read ↗

The Clustered DNA Lesions – Types, Pathways of Repair and Relevance to Human HealthSemantic proximity Read ↗

Role of DNA damage and repair in radiation cancer therapy: a current update and a look to the futureSemantic proximity Read ↗

Sensing and repairing DNA double-strand breaks.Semantic proximity Read ↗

What Does the History of Research on the Repair of DNA Double-Strand Breaks Tell Us?—A Comprehensive Review of Human RadiosensitivitySemantic proximity Read ↗

Pathways of DNA double-strand break repair and their impact on the prevention and formation of chromosomal aberrationsSemantic proximity Read ↗

Induction and Repair of Clustered DNA Lesions: What Do We Know So Far?Semantic proximity Read ↗

Molecular Targets in Cellular Response to Ionizing Radiation and Implications in Space Radiation ProtectionSemantic proximity Read ↗

Biological consequences of formation and repair of complex DNA damage.Semantic proximity Read ↗

DNA Damage Clustering after Ionizing Radiation and Consequences in the Processing of Chromatin BreaksSemantic proximity Read ↗

Key molecular DNA damage responses of human cells to radiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.