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Article

Molecular Targets in Cellular Response to Ionizing Radiation and Implications in Space Radiation Protection

1 Jan 2002

Abstract excerpt

DNA repair systems and cell cycle checkpoints closely co-operate in the attempt of maintaining the genomic integrity of cells damaged by ionizing radiation. DNA double-strand breaks (DSB) are considered as the most biologically important radiation-induced damage. Their spatial distribution and association with other types of damage depend on radiation quality. It is believed these features affect damage...

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PMID: 12793724
DOI: 10.1269/jrr.43.s13

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