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Article

Incoherent feed-forward regulatory logic underpinning glucocorticoid receptor action.

Proceedings of the National Academy of Sciences of the United States of America - 29 Jan 2013

Chen Sheng-Hong, Masuno Kiriko, Cooper Samantha B, Yamamoto Keith R

Abstract excerpt

The complexity and specificity of metazoan transcription are determined by combinatorial control of the composition and activity of regulatory complexes. To investigate the basis of this specificity, we focused on the glucocorticoid receptor (GR), a single regulatory factor that integrates multiple signals to give rise to many distinct patterns of expression. We measured the expression of a set of genes, each...

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Identifiers

PMID: 23307810
DOI: 10.1073/pnas.1216108110
PMCID: PMC3562826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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