Article
LMP1 promoter sequence analysis in Epstein Barr virus pediatric infection reveals preferential circulation of B95.8 related variants in Argentina.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2013
Gantuz Magdalena, Lorenzetti Mario Alejandro, Altcheh Jaime, De Matteo Elena, Moscatelli Guillermo, Moroni Samanta, Chabay Paola Andrea, Preciado María Victoria
Abstract excerpt
The Epstein Barr virus (EBV) is associated with several lymphoid and epithelial malignancies such as Hodgkin and Burkitt lymphoma or nasopharyngeal carcinoma and it is also the etiological agent of infectious mononucleosis (IM). Transcriptional regulation of the viral oncoprotein LMP1, remains yet not fully understood. LMP1 expression can be initiated in an EBNA2 dependent or independent manner from ED-L1 or...
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