Article
EBNA1 sequences in Argentinean pediatric acute and latent Epstein-Barr virus infection reflect circulation of novel South American variants.
Journal of medical virology - 1 Oct 2010
Lorenzetti Mario Alejandro, Altcheh Jaime, Moroni Samanta, Moscatelli Guillermo, Chabay Paola Andrea, Preciado María Victoria
Abstract excerpt
Epstein-Barr virus (EBV) is related to the development of lymphomas and is also the etiological agent for infectious mononucleosis (IM). Sequence variation of the EBNA1 gene, consistently expressed in all EBV-positive cells, has been widely studied. Based on the amino acid at codon 487 five major EBNA1 variants have been described, two closely related prototypic variants (P-ala and P-thr) and three variant...
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