Article
Structural variability of the carboxy-terminus of Epstein-Barr virus encoded latent membrane protein 1 gene in Hodgkin's lymphomas.
Journal of medical virology - 1 Nov 2007
Guiretti Deisy M, Chabay Paola A, Valva Pamela, Stefanoff Claudio G, Barros Mário H M, De Matteo Elena, Renault Ilana Zalcberg, Preciado Maria Victoria, Hassan Rocio
Abstract excerpt
Epstein-Barr virus (EBV) is implicated in the pathogenesis of several lymphoid and epithelial neoplasms. Latent membrane protein 1 (LMP1) is the major viral oncogene and it is controversial whether tumor LMP1 variants reflect their geographical predominance or are associated with enhanced oncogenic properties. This study aimed to analyze LMP1 molecular variability of 62 EBV+ Hodgkin's lymphomas and 22...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
