Article
Epstein-barr virus (EBV) in healthy carriers: Distribution of genotypes and 30 bp deletion in latent membrane protein-1 (LMP-1) oncogene.
Journal of medical virology - 1 Aug 2004
Correa Rita Mariel, Fellner María Dolores, Alonio Lidia Virginia, Durand Karina, Teyssié Angélica R, Picconi María Alejandra
Abstract excerpt
There are two types of Epstein Barr virus (EBV): EBV-1 and EBV-2, distinguished by genomic polymorphism in the genes encoding the nuclear antigens (EBNA-2, -3A, -3B, -3C). Latent membrane protein 1 (LMP-1) is an EBV protein with known oncogenic properties. Different variants had been described; among them, a 30 base pair (bp) deletion (del-LMP-1) had been reported in benign and malignant pathologies, but there is...
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