Article
The Wilhelmine E. Key 1986 invitational lecture. Fifty years of genetic load.
The Journal of heredity - 1 Jan 2000
Wallace B
Abstract excerpt
The author's involvement with and his successive reactions to the genetic load concept [whose beginning is identified with Haldane's paper. The effect of variation on fitness] is presented in the form of a personal odyssey. The major change in attitude involved the realization that the density- and frequency-independent selection discussed by most population geneticists has little bearing on events transpiring...
Topics
- Animals
- Drosophila melanogaster
- Genetic Variation
- Genetics, Population
- Genotype
- History, 20th Century
- Humans
- Models, Genetic
- Mutation
- Polymorphism, Genetic
- Population Density
- Selection, Genetic