Article
Genetic hitchhiking versus background selection: the controversy and its implications.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 27 Apr 2010
Stephan Wolfgang
Abstract excerpt
The controversy on the relative importance of background selection (BGS; against deleterious mutations) and genetic hitchhiking (associated with positive directional selection) in explaining patterns of nucleotide variation in natural populations stimulated research activities for almost a decade. Despite efforts from many theorists and empiricists, fundamental questions are still open, in particular, for the...
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