Article
HitWalker: variant prioritization for personalized functional cancer genomics.
Bioinformatics (Oxford, England) - 15 Feb 2013
Bottomly Daniel, Wilmot Beth, Tyner Jeffrey W, Eide Christopher A, Loriaux Marc M, Druker Brian J, McWeeney Shannon K
Abstract excerpt
SUMMARY: Determining the functional relevance of identified sequence variants in cancer is a prerequisite to ultimately matching specific therapies with individual patients. This level of mechanistic understanding requires integration of genomic information with complementary functional analyses to identify oncogenic targets and relies on the development of computational frameworks to aid in the prioritization...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.