Decombinator: a tool for fast, efficient gene assignment in T-cell receptor sequences using a finite state machine

Abstract excerpt

SUMMARY: High-throughput sequencing provides an opportunity to analyse the repertoire of antigen-specific receptors with an unprecedented breadth and depth. However, the quantity of raw data produced by this technology requires efficient ways to categorize and store the output for subsequent analysis. To this end, we have defined a simple five-item identifier that uniquely and unambiguously defines each TcR...

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