Article
IMSEQ—a fast and error aware approach to immunogenetic sequence analysis
18 May 2015
Abstract excerpt
MOTIVATION: Recombined T- and B-cell receptor repertoires are increasingly being studied using next generation sequencing (NGS) in order to interrogate the repertoire composition as well as changes in the distribution of receptor clones under different physiological and disease states. This type of analysis requires efficient and unambiguous clonotype assignment to a large number of NGS read sequences, including...
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