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Article

Reactive oxygen species by isoflurane mediates inhibition of nuclear factor κB activation in lipopolysaccharide-induced acute inflammation of the lung.

Anesthesia and analgesia - 1 Feb 2013

Chung In Sun, Kim Jie Ae, Kim Ju A, Choi Hyun Sung, Lee Jeong Jin, Yang Mikyung, Ahn Hyun Joo, Lee Sang Min

Abstract excerpt

BACKGROUND: Although anesthetic-induced inhibition of lipopolysaccharide (LPS)-induced lung injury has been recognized, the underlying mechanism is obscure. Some studies suggest that reactive oxygen species (ROS) by isoflurane play a crucial role for anesthetic-induced protective effects on the brain or the heart; however, it still remains controversial. In this study, we examined the role of isoflurane-derived...

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Source

Identifiers

PMID: 23302986
DOI: 10.1213/ANE.0b013e31827aec06

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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