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Article

Reactive oxygen species by isoflurane mediates inhibition of nuclear factor κB activation in lipopolysaccharide-induced acute inflammation of the lung.

Anesthesia and analgesia - 1 Feb 2013

Chung In Sun, Kim Jie Ae, Kim Ju A, Choi Hyun Sung, Lee Jeong Jin, Yang Mikyung, Ahn Hyun Joo, Lee Sang Min

Abstract excerpt

BACKGROUND: Although anesthetic-induced inhibition of lipopolysaccharide (LPS)-induced lung injury has been recognized, the underlying mechanism is obscure. Some studies suggest that reactive oxygen species (ROS) by isoflurane play a crucial role for anesthetic-induced protective effects on the b...

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Source

Identifiers

PMID: 23302986
DOI: 10.1213/ANE.0b013e31827aec06

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-23302986-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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