Randomised trial of a clinical dosing algorithm to start anticoagulation with phenprocoumon.

Abstract excerpt

QUESTION UNDER STUDY: Prospective validation of two algorithms for the initiation of phenprocoumon treatment. METHODS: Inpatients with new-onset anticoagulation were randomised to one of two computer assisted dosing algorithms, or to a control arm. The primary outcome measure was the time to achieve therapeutic anticoagulation without overshooting (INR >4.0 within 10 days). Secondary outcomes included...

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