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Article

Epidemiology of HBV S-gene mutants in the Liguria Region, Italy: Implications for surveillance and detection of new escape variants.

Human vaccines & immunotherapeutics - 1 Mar 2013

Sticchi Laura, Caligiuri Patrizia, Cacciani Roberto, Alicino Cristiano, Bruzzone Bianca

Abstract excerpt

HBV surface antigen (HBsAg) variants may impair diagnosis or allow the virus to escape vaccine-induced immunity and their circulation in the population can represent a Public Health threat. Their prevalence, however, is not yet completely established. Evidence indicates that amino acid substitutions within HBsAg can lead to conformational changes which allow mutated HBV to escape the vaccine-induced antibodies...

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Source

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Identifiers

PMID: 23296324
DOI: 10.4161/hv.23236
PMCID: PMC3891713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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